One of genital diseases or chronic bacterial infections of genital area that is transmitted mainly through sexual contact is Granuloma Inguinale or otherwise said: Donovanosis, granuloma genital ulcer, genital-inguinal granuloma. This disease is highly contagious, has chronic and slow progress, being detected for the first time in India, in 1882 and then, in 1905, the physician Colonel Charles Donovan identifying the intracellular corpus incriminated in causing the disease.

This disease occurs mostly in people living in subtropical and tropical climates, being considered a relatively rare disease. In European countries it appear less, most of the cases being reported in the Caribbean, South Africa, New-Guinea, Brazil and Africa. According to statistics it seems to occur more often in men (10 times more than women), it is more common in gay persons and less common in heterosexuals. The infection is transmitted quite easily from the sick person to the healthy one through unprotected sexual intercourse.


Symptoms. After contamination, the incubation period of the pathogen is carried from one week to 50 days. Pathogens are called, "Donovan bodies" and can occur together with other bacteria, including bacteria such as Calymmatobacter granulomatis (about which there are knows quite a few things), HIV or bacteria causing syphilis or gonorrhea.

This infection is manifested by ulcers in the skin surface, but also on lymphatic structures found in the groin, anus and genitals. In men such infection can affect the whole penis, and vulva in women.

At first, it may be seen only one bump on the skin that resembles a pea. Then it swells, turns red, it does not hurt, but when it gets infected, ulcerations occur and pain is installed. The area has a smooth surface and irregular edges. Gradually it increases and spreads over a larger area on the skin. Ulcers also develop in the anal canal or all around it.

In the groin, due to infection and proliferation of tissue granulation, a kind of subcutaneous nodules get formed. In the vulva, nodules or painless papules may appear, with size of approx. 3 cm.

Without treatment the disease worsens, the infection destroys genital tissue and then spreads to other areas of the body, reaching the lymph nodes, where it triggers liver infection.


Diagnosis. Diagnosing is made by visual examination of lesions and after analysis of symptoms that the infected person accuses. To be sure it is Donovanosis, your doctor may recommend additional tests to be conducted such as:
-collection of samples from the lesion for their analysis in the laboratory;
-achievement of a biopsy (removing a tissue sample from the lesion);
-to exclude the diagnosis of syphilis, the doctor has available also the option of a blood test. Donovanosis can be confused with secondary syphilis and in completely unfortunate cases, the infection with syphilis infection may overlap to the donovanosis infection. That is another bonus disease... as a promo!


Treatment. Doctors generally recommend drug therapy based on antibiotics. They are drawn according to the state of the patient, the type and severity of infection, but also age.

Antibiotics and sulfonamides are used in the form of lotions and powders. These are administrated only after the area was thoroughly disinfected.

Medications are administered only at the prescription of a physician. It is very important that treatment be supplemented with vitamin and mineral supplements to strengthen the body's immune system. Usually, after antibiotic treatment, results occur in a week, and after 3-5 weeks total healing occurs.